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I received a grant from
2019-06-01
I received a grant from The Kendeda Fund to write and promote my book, , on which this comment is based. I thank Richard King (Chatham House, London, UK) for data assistance, Christian Guthier (All is Possible, Oxford, UK) for graphic design, and Sarah Cornell (Stockholm Resilience Centre, Stockholm
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mao inhibitors list What lies ahead Clearly the
2019-06-01
What lies ahead? Clearly the extremely ambitious goals and targets set by the UNCoLSC have not been reached, and challenges must be overcome. While the current evaluation highlights several challenges and strategies for action, a clear process in moving forward would be to link this bottleneck analy
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People in LMICs are disproportionately exposed to severe acu
2019-06-01
People in LMICs are disproportionately exposed to severe acute kidney injury and have substantially less access to effective treatment than do people in higher-income countries. Framing acute kidney injury as a driver of substantial inequity in disease risk and mortality in low-resource countries, t
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br Methods The study population comprised patients
2019-06-01
Methods The study population comprised 150 patients who underwent implantations of Medtronic dual chamber pacemakers and who had maintained both atrial and ventricular sensing (either in DDD, DDI, or VDD modes) from March 2008 to October 2010. The implanted carboxypeptidase b generators were eit
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rosmarinic acid To date only one study regarding the role of
2019-06-01
To date, only one study regarding the role of miRNAs during hepatic cyst formation has been published. While this is an older publication, published in 2008, the findings are worth discussing, based on the limited information on miRNAs during PLD. In whole liver sections from patients with PLD due t
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br Tara Mangal and colleagues document the struggle to elimi
2019-06-01
Tara Mangal and colleagues document the struggle to eliminate polio in northern Nigeria. However, they overlook the importance of routine immunisation to polio eradication efforts. The investigators identified an association between the risk of contracting polio and oral polio vaccine unavailabil
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We did not identify age
2019-06-01
We did not identify age as a major factor shaping continuing HCV transmission and future seroprevalence. With every blood-borne disease, these epidemiological variables depend on how frequently individuals undergo medical procedures and the risk of acquiring HCV in each case. In our study, we used d
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In Jillian Pintye and colleagues from the Partners PrEP
2019-06-01
In Jillian Pintye and colleagues from the Partners PrEP study team present one of the largest and most comprehensive analyses of syphilis incidence in men and women and the effect of male circumcision. The investigators followed 4716 HIV-1 serodiscordant couples, of whom roughly 50% of the men were
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br Introduction Bone marrow fibrosis is known
2019-06-01
Introduction Bone marrow fibrosis is known to occur in several neoplastic and non-neoplastic conditions. Among neoplastic conditions such as acute leukemia, it is most often seen with acute megakaryoblastic leukemia [1]. Acute promyelocytic leukemia (APL) presenting with marrow fibrosis is a rare
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br Among the most important findings to
2019-06-01
Among the most important findings to have emerged from the massive 2013–16 outbreak of Ebola virus disease in west Africa is the delayed clearance of virus from the semen of men who survived the disease and the consequent risk of sexual transmission of the virus, although this seems to be rare. In
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Bile acids are cholesterol derivatives produced only in the
2019-06-01
Bile acids are cholesterol derivatives produced only in the hepatocytes of the liver. Hepatic bile acid synthesis represents the only quantitatively significant route for cholesterol elimination. Bile acids are amphipathic physiological detergents that facilitate dietary cholesterol, lipid and fat-s
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The distribution of dental treatments
2019-05-31
The distribution of dental treatments and the number of treated teeth within each age group were also analyzed. The 6-years-old group had the lowest mean number of teeth treated by stainless-steel crown (SSC) and the lowest number undergoing pulp therapy (presperidone and, when compared against 201
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Studies and reports of lung metastasis of GCTB
2019-05-31
Studies and reports of lung tgf beta receptor inhibitor of GCTB are rare because of the low incidence of lung metastasis. The biological behavior and clinical features of GCTB are difficult to predict [6,7]. Some researchers have attempted to analyze related clinical factors of lung metastasis, suc
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br Management of warfarin during pacemaker implantable cardi
2019-05-31
Management of warfarin during pacemaker/implantable cardioverter defibrillator insertion Until recently, warfarin use was halted before PM/ICD insertion and the patient was bridged with intravenous (IV) unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH) if the thromboembol
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The aim of this cross sectional study was
2019-05-31
The aim of this cross-sectional study was to investigate the relationships between patient characteristics and antithrombotic therapy prescribed for the prevention of ischemic stroke and systemic embolism in patients with NVAF in clinical practice. Additionally, because the data were to be used to c
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