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The metal exposures with Cd and Cu revealed
2020-07-29
The metal exposures with Cd and Cu revealed sensitivity of T-ChE and Es-ChE activity in Saccostrea at concentrations > 100µg/L Cd, most notably so in digestive gland, where activities of both enzyme fractions decreased nearly 3-fold relative to controls at the highest exposure concentration (1000µg/
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Spirogyra neglecta SN is an edible freshwater
2020-07-29
Spirogyra neglecta (SN) is an edible freshwater macroalga and a common ingredient used in Northern Thai cuisine. SN contains many nutritional constituents including fat, proteins, carbohydrate, fibers, multivitamins, minerals, and antioxidants. In addition, it has been reported to exhibit antigastri
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A role for the E E interface
2020-07-28
A role for the E2–E3 interface in governing mono- versus polyubiquitination is not mutually exclusive with that of the E2 backside, which has previously been shown to mediate polyubiquitination through its ability to bind to Ub [21], [25], [33]. Brzovic and colleagues first demonstrated the importan
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Overall the above reported preclinical evidence
2020-07-28
Overall, the above reported preclinical evidence suggests that DDP-4is may offer renoprotective (and cardioprotective) effects in the context of hypertension and other disorders of sodium retention via both incretin-dependent and independent mechanisms. Furthermore, it is likely that long-term DDP-4
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DNA PK is a heterotrimeric complex consisting of the catalyt
2020-07-28
DNA-PK is a heterotrimeric complex consisting of the catalytic subunit DNA-PKcs and a heterodimer of Ku70 and Ku80. DNA-PK binds dsDNA breaks and functions in non-homologous end joining (NHEJ) (Pannunzio et al., 2018) and also in DNA sensing, upregulating type I IFN and cytokines via the STING pathw
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pde inhibitor DHFR deficient Chinese hamster ovary CHO DHFR
2020-07-28
DHFR-deficient Chinese hamster ovary (CHO DHFR−) pde inhibitor are one of the most popular mammalian expression system for inducible amplification of transgene. Target gene is generally subcloned into vectors containing the dihydrofolate reductase (DHFR) gene which serves as the selective marker ge
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Significant potential differences among pesticide enantiomer
2020-07-28
Significant potential differences among pesticide enantiomers may warrant registration of a single enantiomer product or an enriched mixture of the active enantiomer instead of the racemic mixture (Liu and Tang, 2011). In Switzerland and the Netherlands, DMOG synthesis like mecoprop and dichlorprop
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Radioligand selection may be the critical factor for detecti
2020-07-28
Radioligand selection may be the critical factor for detecting CRF1 receptor antagonists that bind to the ECD. Compounds with this site of action could be useful starting points for developing therapeutic agents with improved physical properties over J-site antagonists. However, it remains to be see
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CPA was not observed to have antagonistic activity against
2020-07-28
CPA-7 was not observed to have antagonistic activity against S. enterica under MAP at 5 ± 1 °C, and no pathogen growth was observed. Similarly, Alegre et al. (2013a) did not observe an antagonistic effect against Salmonella on apple wedges. Regarding L. monocytogenes, we observed an antagonistic eff
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The binary interaction parameters were then
2020-07-28
The binary interaction parameters were then estimated for all the binary systems involved in the ternary or quaternary systems. References for experimental data, the values of fitted and the average absolute relative deviation (AARD) are shown in Table 3. Mainly for the cosolvent – solute systems a
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5003 In the proposed language a concrete architectural
2020-07-28
In the proposed language, a concrete architectural model consists of a set of individual components (ConcreteComponent) and a set of relationships (Relationship) among them. Each component has a type, defined by ComponentType. The container component type identifies a component that contains other c
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SCR 7 Motor learning and control require
2020-07-28
Motor learning and control require many cognitive functions associated with the COMT Val158Met polymorphism. Thus, an association between this polymorphism and motor behavior is expected. For instance, working memory (WM) is one of the cognitive functions associated with COMT. Spatial working memory
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Regarding the COMT haplotype and MDD
2020-07-28
Regarding the COMT haplotype and MDD treatment response, a previous study of haplotype C-C-A of exonic SNPs, rs4633, rs4818, and rs4680 correlated the treatment response phenotypes, and detected haplotype CCA more often in responders than non-responder and controls (Kocabas et al., 2010). In our stu
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The development and physiology of cartilage
2020-07-28
The development and physiology of cartilage and bones are highly similar in mammals and teleosts validating the zebrafish as a reliable vertebrate model in this field [22]. Expression of genes and the molecular pathways involved in the endochondral ossification are well conserved. For instance, as i
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Diabetes mellitus and insulin resistance are disorders
2020-07-28
Diabetes mellitus and Poziotinib mg resistance are disorders that require careful and controlled care considering the use of specific medications, such as the administration of exogenous insulin (type 1 diabetes) or oral hypoglycemic agents (type 2 diabetes and/or insulin resistance) that stimulate
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