• br Discussion In this pilot

  2019-06-27

  

  Discussion In this pilot study, we report that sequential treatment of low dose clofarabine and lenalidomide is safe and feasible for elderly patients with high risk MDS and AML. Only one subject developed dose limiting toxicity (liver dysfunction) from lenalidomide consolidation therapy. Pre-tre

• br Conclusion br Source of funding br Acknowledgement

  2019-06-27

  

  Conclusion Source of funding Acknowledgement Arsenic is widely dispersed throughout nature, and its toxic effect in humans, which focus mainly on somatic cells, as well known. Epidemiological research and in vitro testing have shown that long-term contact with arsenic can induce the forma

• The study by Mijiti and colleagues also illustrates that bes

  2019-06-27

  

  The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai

• br Results We evaluated MM

  2019-06-26

  

  Results We evaluated 148 MM patients, 87 women and 61 men, age range 29–69 years, 58 of whom developed bacteremia during the early post-transplant period (Table 1). The genotypes were in Hardy–Weinberg equilibrium. We did not observe any statistically significant association between the genotypes

• The communities on both sides of

  2019-06-26

  

  The communities on both sides of the South Sudan–Uganda border share the risk of sleeping sickness, as transmission of still occurs in this T 705 region. Most of the South Sudanese refugees come from endemic areas and have been accommodated in multiple camps in Adjumani and Yumbe districts, where

• br Discussion Prehabilitation is a program to

  2019-06-26

  

  Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and

• El poema arranca de una

  2019-06-26

  

  El poema arranca de una contemplación del paisaje en pleno mes de noviembre. El “verdor” de las siemprevivas contrasta con un panorama vegetal dominado por la “grisura” de la deshojadura otoñal. La mirada del yo poético se fija preferentemente “en las siemprevivas y en las plantas perennes”. Esta pe

• The comparative consensus modelling approach used by

  2019-06-26

  

  The comparative consensus modelling approach used by Eaton and colleagues is now used frequently to justify the implementation of particular HIV interventions. However, this approach produces meaningful results only if the comparison is based on valid models. Most comparative consensus studies (incl

• Universalisation means reaching all individuals with good

  2019-06-26

  

  Universalisation means reaching all individuals with good quality, effective interventions without financial hardship. Coverage matters. Participatory women\'s groups are effective in reducing newborn mortality among poor populations provided they involve about 30% of pregnant women in the populatio

• Al observar las cuatro constituciones Brasil

  2019-06-26

  

  Al observar las cuatro constituciones (Brasil, Argentina, Paraguay y Uruguay) se destaca una ejemplar redacción del Artículo 47 de la Constitución de Uruguay, al definir cuál es la prioridad en el uso del recurso además de determinar no sólo la participación social en la planificación de estrategias

• br Case report A year old female presented

  2019-06-25

  

  Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (Rivaroxaban of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin; vincisti

• In the past decade preclinical studies have addressed the

  2019-06-25

  

  In the past decade, preclinical studies have addressed the putative role of non-coding RNAs in tumorigenesis, metastasis and therapy response in osteotropic cancers. Besides long non-coding RNAs, microRNAs (miRs) represent a class of small non-coding RNAs, (18–25 nucleotides long), that regulate pro

• Riluzole Introduction Cancer therapy has evolved throughout

  2019-06-25

  

  Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of

• In contrast the prevalence of BS or Brugada type

  2019-06-25

  

  In contrast, the prevalence of BS or Brugada-type ECG in Asian countries is relatively high. Type 1 ECG has been identified in 0.17% of 3907 asymptomatic Filipinos [24] and in 0.13% of 20,652 Taiwanese patients who visited the hospital for non-cardiovascular reasons [25]. Brugada-type ECG has been o

• br The translational pipeline in biomedicine

  2019-06-25

  

  The translational pipeline in biomedicine (from bench to bedside) focused the attention of the global research CGS 21680 on delivery of results to patients. The notion was rapidly accepted, as shown by the training of researchers in translational approaches, the establishment of translational rese

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